Charles Burns:
The first comic I ever read by Burns was Black Hole, which is all about high school drama and creepy alien STDs. I love his slick, precise style of inking and all of the weird creepy stuff he throws into his comics (which I really need to read more of...)
Sophie Campbell:
I fell in love with Campbell's series Wet Moon way back in high school. It was the perfect combination of slice of life and weirdo small town/Twins Peaks style horror. Plus her art is gorgeous! Now she's been working on mainly licensed comics (and kicking butt at them) but I hope she returns to indie comics one day.
Bernie Wrightson:
Wrightson is the only artist here whose work I haven't read. He got his start doing horror comics but eventually left to pursue illustration (also because he wanted his work to remain in black and white but his publishers would wreck his lifework with color). I found a poster of one of his illustrations from Frankenstein and I was hooked! What amazing composition and inking. I really ought to track down a copy of Frankenstein with his work in it...
(the fateful image itself!)